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          June, 2019, Songhai’s proteomic study on EMC function has been accepted at Cell Report!?

          May, 2019,?Pyung-Gang Lee?joined us as a postdoctoral fellow, welcome!?

          April, 2019, Liang, Songhai, and Jie’s manuscript on identification of C. difficile toxin A receptors has been accepted at Nature Microbiology, congratulations!?

          Jan, 2019, Eason’s paper on developing novel genetically encoded K+ ion sensors has been accepted at Communication Biology, congratulations!?

          Jan, 2019, our joint research with Ipsen on developing a new class of engineered therapeutic toxins has been accepted at Science Advances,?congratulations!

          Oct., 2018, Songhai’s paper on genome-wide screens for Shiga toxins and Ricin is accepted at PloS Biology, congratulations!?

          Sept., 2018, Xiaozhe joined us from Tsinghua University, welcome. ?

          Sept., 2018, Three people moved on from our lab: Liang starts his own lab at the newly formed Westlake Institute for Advanced Study; Sulyman joined Broad Institute of Harvard/MIT. Quan finished his study here and moved back to his previous PI position in China. We wish them all the best!?

          August, 2018, Ji joined us from Dartmouth College, welcome.?

          June, 2018, Aina is awarded St. Baldrick Foundation International Scholar. It comes with a 3-year grant to fund her cancer research in the U.S. and in China. Congratulations!?

          April, 2018, Liang has another paper accepted at Science, congratulations!

          March, 2018, We received an industry sponsored funding, an R21, and an R01, a great year for us!?

          Feb., 2018,?Linxiang joined our lab from Iowa, welcome!

          Feb., 2018, Sicai’s paper on new botulinum neurotoxin-like toxin is published on Cell Host and Microbe. Congratulations!

          Oct., 2017, David Baker’s group’s new protein design paper was acceptd at Nature, Shin in the lab is one of the author. Congratulations!

          Sept., 2017: Dr. Quan Wu joined our lab as a visiting scholar. Welcome!

          August, 2017: Sicai’s paper on ganglioside-binding mechanism was accepted at Nature Communications. Congratulations!

          June, 2017: George Church’s lab teamed up with us and got the funding from Office of National Intelligence on developing new methods to detect toxins. Cheers!?

          April, 2017: Liang and Lisheng’s paper on engineering botulinum neurotoxin was accepted at Nature Communications. Congratulations!

          Feburary, 2017: Dr. Aina He joined our lab as a visiting scholar. Welcome!

          January, 2017: Time magazine published a cover story on medical use of botulinum neurotoxins. Min and Ed were quoted. http://time.com/magazine/us/4623396/january-16th-2017-vol-189-no-3-u-s/

          January, 2017:?Sicai’s paper on identification and characterization of a new botulinum neurotoxin has been accepted at Nature Communications. Congratulations!?

          September 2016: Liang and Jie identified Frizzled as a receptor for C. difficile toxin B through CRISPR-Cas9 mediated?genome-wide screen. Their ?paper is published on Nature as an article. Congratulations!




          June, 2016: Min is selected as one of 10 researchers to receive the 2016 Investigators in the Pathogenesis of Infectious Disease Award from the Burroughs Wellcome Fund! Congratulations! See news on HMS website:?



          June 2016: Congratulations to Dr. Sicai Zhang for his new paper accepted at Nature Structure & Molecular Biology!?Also featured in ?“News and Views” Nature Structure & Molecular Biology, 2016, 23:619-621.

          Feb, 2016: Dr. Miyashita joined the lab as a postdoctoral fellow. Welcome!

          Oct., 2015: We joined Boston Children’s Hospital and the lab is relocated to the Enders research building on Longwood Ave.

          Oct., 2015: Congratulations to Dr. Xiaofen Zhang for getting the “100 talents” program position at Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences?

          April, 2015: We are in Harvard News:


          April, 2015: Dr. Eason Shen and Sulyman Barkho joined the lab as postdoctoral fellows. Welcome!

          Feb, 2015: Dr. Songhai Tian joined the lab as a postdoctoral fellow. Welcome!

          Sept., 2014: Dr. Jie Zhang joined the lab as our lab manager. Welcome!

          August, 2014: Dr. Sicai Zhang joined the lab as a postdoctoral fellow. Welcome!

          July, 2014: Congratulations to Prof. Lisheng Peng for getting a distinguished faculty position in China:? Professor and “100 talent”, the third affiliated hospital , Sun Yat-Sen university, China. We are sad that Lisheng is leaving us, but very happy for his new independent position in China!

          June. 2014: Dr. Christopher Boone joined the lab as a postdoctoral fellow. Welcome!

          Feb. 2014: Congratulations to Dr. Lisheng Peng for his promotion to the junior faculty rank of Instructor at the Dept. of Microbiology and Immunobiology of Harvard Medical School.

          Oct., 2013: Dr. Liang Tao joined the lab as a postdoctoral fellow. Welcome!

          May 2013: Congratulations to Dr. Lisheng Peng, who received the Roger T. Kelleher Award for his recent paper on botulinum neurotoxin receptors.? This is his second win of this award for excellent research paper of the year.

          April 2013: We received our first R01 award from NINDS!

          March 2013: We are in Harvard News: “A New Wrinkle for Botox”:


          Feb. 2013: Our paper on cytotoxicity of botulinum neurotoxins was published on Nature Communications:


          ? Dong Lab updated July 2016 ?